Author

M. S. Downey

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Cell Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

A. Brumwell· 1 shared B. J. Backes· 1 shared D. Sheppard· 1 shared F. R. Papa· 1 shared H. A. Chapman· 1 shared J. J. Kathiriya· 1 shared M. Thamsen· 1 shared T. A. Wenger· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperCell Biology

A. Brumwell

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1 paper

Recent·Most cited

Cell BiologybioRxivSep 16, 2021

IRE1α drives lung epithelial progenitor dysfunction to establish a niche for pulmonary fibrosis

V. C. Auyeung, M. S. Downey, J. J. Kathiriya…·F. R. Papa

This study shows that IRE1α inhibition reduces ER stress and TGFβ signaling in lung epithelial cells, decreasing fibrosis by targeting damage-associated progenitors.

DOI 10.1152/ajplung.00408.2021

mousebulk RNA-seq

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