Author

M. Sahin-Toth

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Biophysics· 1

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Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

D. Kozakov· 1 shared I. Kolossvary· 1 shared S. Vajda· 1 shared Z. Sun· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiophysics

D. Kozakov

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintAug 21, 2020

The N34S mutation of SPINK1 may impact the kinetics of trypsinogen activation to cause early trypsin release in the pancreas

Z. Sun, I. Kolossvary, D. Kozakov…·S. Vajda

The paper shows that the N34S mutation in SPINK1 reduces its inhibitory efficiency, leading to earlier trypsin release in the pancreas due to kinetic effects and autocatalytic conversion.

DOI 10.1101/2020.08.21.262162

humanprotein structure

𝕏 PostBluesky