Author

M. Sandy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:metabolomics· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Organism:human· 1

Frequent Co-Authors

T. S. Kyaw· 2 shared A. N. Goga· 1 shared A. Venook· 1 shared B. G. H. Guthrie· 1 shared C. Atreya· 1 shared D. Gempis· 1 shared E. Bess· 1 shared E. L. van Blarigan· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

T. S. Kyaw

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Human gut Actinobacteria boost drug absorption by secreting P-glycoprotein ATPase inhibitors

T. S. Kyaw, M. Sandy, K. Trepka, J. Goh, K. Yu, V. Dimassa, E. Bess, J. Bisanz, P. J. Turnbaugh

The gut bacterium Eggerthella lenta secretes inhibitors of P-glycoprotein ATPase activity, accelerating drug absorption.

bioRxiv · Oct 13, 2022Microbiology

A conserved enzyme found in diverse human gut bacteria interferes with anticancer drug efficacy

P. Spanogiannopoulos, T. S. Kyaw, B. G. H. Guthrie, P. H. Bradley, J. V. Lee, J. Melamed, Y. N. A. Malig, K. N. Lam, D. Gempis, M. Sandy, W. Kidder, E. L. van Blarigan, C. Atreya, A. Venook, R. R. Gerona, , P. Turnbaugh

The paper shows that a conserved enzyme in gut bacteria inactivates anticancer drugs, reducing their efficacy in mice and highlighting microbial contributions to drug metabolism.

bioRxiv · May 2, 2022 · PreprintMicrobiology