Author

M. Schvartzman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

A. Edri· 2 shared A. Porgador· 2 shared G. Le Saux· 2 shared U. Hadad· 2 shared A.-S. Smith· 1 shared C. Di Primo· 1 shared E. Toledo· 1 shared L. Li· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersImmunology

A. Edri

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Molecular Scale Spatio-Chemical Control of the Activating-Inhibitory Signal Integration in NK Cells

E. Toledo, G. Le Saux, L. Li, M. Rosengenrg, Y. Keidar, V. Bhingradive, A. Edri, U. Hadad, C. Di Primo, T. Buffeteau, A.-S. Smith, A. Porgador, M. Schvartzman

This study uses a nanoengineered cell niche to investigate how spatial positioning of activating and inhibitory ligands affects NK cell signaling, finding that a 40 nm gap optimally inhibits NKG2D signaling via KIR2DL1.

bioRxiv · Mar 24, 2020Immunology

Mechanical Regulation of the Cytotoxic Activity of Natural Killer Cells

L. Mordechay, A. Edri, U. Hadad, A. Porgador, M. Schvartzman, G. Le Saux

This paper shows that NK cells modulate their cytotoxic activity in response to surface stiffness, with a bell-shaped response peak at ~few hundreds of kPa, and links this to DAP10 clustering and a catch-bond model.

bioRxiv · Mar 2, 2020Immunology