Cancer BiologybioRxiv
Defining and targeting adaptations to oncogenic KRASG12C inhibition using quantitative temporal proteomics
N. Santana-Codina, A. S. Chandhoke, Q. Yu…·J. D. Mancias
This study uses quantitative temporal proteomics to analyze KRASG12C inhibitor responses in cancer models, identifying effective drug combinations to overcome resistance.
DOI 10.1016/j.celrep.2020.03.021