Adipocyte lipolysis abrogates skin fibrosis in a Wnt/DPP4-dependent manner
A. R. Jussila, E. Caves, B. Zhang, S. Kirti, M. Steele, V. Lei, E. Hamburg-Shields, J. Lydon, Y. Ying, R. Lafyatis, S. Rajagopalan, V. Horsley, R. P. Atit
This study shows that adipocyte lipolysis, regulated by Wnt signaling and DPP4, reduces skin fibrosis by modulating ECM homeostasis.
bioRxiv · Jan 21, 2021 · PreprintCell Biology