Pharmacology & ToxicologybioRxiv
KD-64 - a new selective A2A adenosine receptor antagonist has anti-inflammatory activity but contrary to the non-selective antagonist - caffeine does not reduce diet-induced obesity in mice
M. Kotanska, A. Dziubina, M. Szafarz…·K. Kiec-Kononowicz
KD-64, a selective A2A adenosine receptor antagonist, shows anti-inflammatory effects and improves glucose tolerance in obese mice, unlike caffeine which does not reduce obesity but increases inflammation markers.
DOI 10.1371/journal.pone.0229806