ImmunologybioRxiv
Macrophages inhibit Coxiella burnetii by the ACOD1-itaconate pathway for containment of Q fever
L. Kohl, N. A. A. Siddique, B. Bodendorfer…·R. Lang
This study identifies the ACOD1-itaconate pathway in macrophages as critical for restricting Coxiella burnetii replication and proposes it as a therapeutic target for Q fever.