Enhanced extracellular matrix remodeling due to embedded spheroid fluidization
T. Zhang, S. Ameen, S. Ghosh, K. Kim, M. Thanh, A. E. Patteson, M. Wu, J. M. Schwarz
This study uses a computational model to show that fluid-like tumor spheroids cause more ECM remodeling than solid-like spheroids due to shape fluctuations and cellular motility.
bioRxiv · Mar 25, 2024Biophysics