Xrp1 governs the stress response program to spliceosome dysfunction
D. Stankovic, L. Tain, M. Uhlirova
The paper shows that Xrp1-Irbp18 drives a stress response to U5 snRNP dysfunction, promoting cell cycle arrest and apoptosis while splicing defects remain unresolved.
bioRxiv · Apr 6, 2023Cell Biology