Cell BiologybioRxiv
NuMA deficiency causes micronuclei via checkpoint-insensitive k-fiber minus-end detachment from mitotic spindle poles
M. v. Toorn, A. Gooch, S. Boerner, T. Kiyomitsu
This study shows NuMA deficiency causes micronuclei through k-fiber minus-end detachment from spindle poles, which bypasses the mitotic checkpoint and leads to genomic instability.
DOI 10.1016/j.cub.2022.12.017