BiochemistrybioRxiv
Stability of ligand-induced protein conformation influences affinity in maltose-binding protein
M. van der Noort, M. de Boer, B. Poolman
The paper shows that altering the stability of ligand-bound conformations can change ligand affinity in maltose-binding protein, beyond modifying binding site residues.
DOI 10.1016/j.jmb.2021.167036