Author

M. Varma-Basil

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

K. Bhattacharyya· 2 shared M. Bose· 2 shared V. Brahmachari· 2 shared V. Nemaysh· 2 shared A. M. Lynn· 1 shared A. Prakash· 1 shared A. Singh· 1 shared K. Natarajan· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersMicrobiology

K. Bhattacharyya

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Author profile →

2 papers

Recent·Most cited

Modulation of macrophage defense responses by Mycobacterial persistence protein MprA (Rv0981) in human THP-1 cells: effect of single amino acid variation on host-pathogen interactions

K. Bhattacharyya, U. Bandopadhyay, A. Singh, A. Prakash, V. Nemaysh, S. Jain, M. Varma-Basil, A. M. Lynn, M. Bose, P. M. Luthra, K. Natarajan, V. Brahmachari

This study shows that the MprA variant G70S in M. tuberculosis reduces phago-lysosome fusion and increases immune suppressive cytokines in THP-1 macrophages, supporting pathogen persistence.

bioRxiv · Apr 27, 2020 · PreprintMicrobiology

Correlation of drug resistance with Single Nucleotide Variations through genome analysis and experimental validation in a multi-drug resistant clinical isolate of M.tuberculosis.

K. Bhattacharyya, V. Nemaysh, M. Joon, R. Pratap, M. Varma-Basil, M. Bose, V. Brahmachari

The paper identifies SNVs in a multi-drug resistant M. tuberculosis isolate and shows their functional impact on drug resistance through genome analysis and experimental validation.

bioRxiv · Mar 7, 2020Microbiology