Pharmacology & ToxicologybioRxiv
Platycodin D prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection in vitro by hindering membrane fusion
T. Y. Kim, S. Jeon, Y. Jang…·C. J. Lee
This study shows that platycodin D inhibits SARS-CoV-2 infection by blocking lysosome- and TMPRSS2-driven entry through membrane cholesterol redistribution.
DOI 10.1038/s12276-021-00624-9