BiochemistrybioRxivPreprint
Identification and Characterization of a B-Raf Kinase Alpha Helix Critical for the Activity of MEK Kinase in MAPK Signaling
D. Nguyen, L. Y. Lin, J. Zhou…·D. Fera
The paper identifies an alpha helix on B-Raf critical for its interaction with MEK and oncogenic activity, suggesting it as a potential drug target for melanoma treatment.
DOI 10.1101/2020.07.19.211177