Dietary sugar type determines the response to protein restriction in females, but not males
Michelle M. Sonsalla, Mari Cole, Madeline Johnson, Samuel Cai, Brenna Virnig, Alexandra Trebil, Reji Babygirija, Julia A. Illiano, Diana Vertein, Yang Liu, Isaac Grunow, Bailey A. Knopf, Sophia Schlorf, Michael Rigby, Chung‐Yang Yeh, , Dudley W. Lamming
The paper shows that in female mice, carbohydrate quality affects metabolic and neurological responses to low protein diets, but not in males.
bioRxiv · Aug 23, 2026 · PreprintPhysiology