Cancer BiologybioRxiv
Disruption of redox balance in glutaminolytic triple negative breast cancer by inhibition of glutamate export and glutaminase
Hoon Choi, Mamta Gupta, Arjun Sengupta…·Rong Zhou
This study shows that inhibiting glutaminase and xCT in TNBC disrupts redox balance, enhances chemotherapy efficacy, and can be monitored non-invasively using PET.
DOI 10.1016/j.neo.2025.101136