Hoon Choi

This study uses [11C]glutamine PET to analyze glutamine metabolism in breast cancer mouse models, revealing subtype-specific metabolic differences and the impact of GLS1 inhibition.

This study shows that inhibiting glutaminase and xCT in TNBC disrupts redox balance, enhances chemotherapy efficacy, and can be monitored non-invasively using PET.

The paper develops a mathematical model to predict pancreatic cancer response to various therapies in mice, showing high accuracy in fitting and predicting tumor dynamics.

This study compares chemotherapy with and without stroma-directed drugs in a mouse model of pancreatic cancer, finding enhanced tumor growth inhibition and changes in tumor microenvironment.