Author

Manon Brenière

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

Alessio BonucciiD· 1 shared Aneel K. AggarwaliD· 1 shared Duc-Duy VuiD· 1 shared Fabien FerrageiD· 1 shared Guillaume BouvigniesiD· 1 shared Jeremy M. StarkiD· 1 shared Ludovic CarlieriD· 1 shared Martin J BlackledgeiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperBiophysics

Alessio BonucciORCID

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1 paper

Recent·Most cited

BiophysicsNature Structural & Molecular BiologyPeer-reviewedJun 19, 2024

Multivalent interactions of the disordered regions of XLF and XRCC4 foster robust cellular NHEJ and drive the formation of ligation-boosting condensates in vitro

Duc-Duy Vu, Alessio Bonucci, Manon Brenière…·Fabien Ferrage

This study characterizes the multivalent interactions of XRCC4 and XLF CTRs, showing they form condensates that enhance DNA ligation in vitro and suggest roles in NHEJ dynamics and cancer biology.

24 citations

humanstructural biology

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