Author

Marco De Cecco

Brown University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

John M. SedivyiD· 2 shared Alexander Y. MasloviD· 1 shared Andrei Gudkov· 1 shared Andrei SeluanoviD· 1 shared Asael Roichman· 1 shared Cristina MontagnaiD· 1 shared Haim Y. Cohen· 1 shared Jan VijgiD· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenomics

John M. SedivyORCID

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2 papers

Recent·Most cited

GenomicsAging BiologyPeer-reviewedJun 29, 2023

Analysis of somatic mutations in senescent cells using single-cell whole-genome sequencing

Lei Zhang, Marco De Cecco, Moonsook Lee…·Jan Vijg

This study uses single-cell whole-genome sequencing to compare mutation burdens in early passage and deeply senescent human fibroblasts, finding increased single-nucleotide variations and aneuploidies in senescent cells.

10 citations

humanwhole-genome sequencing

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Molecular BiologybioRxivPreprintNov 4, 2018

Inhibition of retrotransposition improves health and extends lifespan of SIRT6 knockout mice

Matthew Simon, Michael Van Meter, Julia Ablaeva…·Vera Gorbunova

This study shows that inhibiting L1 retrotransposition with NRTIs improves health and extends the lifespan of SIRT6 knockout mice by reducing type I interferon response and DNA damage.

DOI 10.1101/460808

mouseexperimental assay

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