BioinformaticsBiophysical JournalPeer-reviewed
Towards Understanding the Drivers of Antibody-Antigen Binding
Omeir Khan, Marcus Kankkunen, Michel Shaker…·Diane Joseph‐McCarthy
The paper uses FTMap to analyze 50 antibody-antigen complexes, finding that paratopes are hot spot-rich and that Trp/Tyr residues drive hot spot formation.
DOI 10.1016/j.bpj.2026.02.008