Cancer BiologybioRxivPreprint
Nitric oxide-dependent inflammation underlies Notch and PI3K/Akt oncogene cooperation
Santiago Nahuel Villegas, Rita Gombos, Irene Gutiérrez Pérez…·Maria Dominguez
This study identifies nitric oxide synthase (NOS) and lipoxygenase (LOX) as druggable targets that suppress Notch-PI3K/Akt oncogene cooperation in Drosophila without side effects.
DOI 10.1101/174169