Author

Mark R. Ambroso

Elements Biosciences (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Assay:scRNA-seq· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Andrew Altomare· 2 shared Bryan R. LajoieiD· 2 shared Matthew William Kellinger· 2 shared Semyon KruglyakiD· 2 shared Shawn LevyiD· 2 shared Vivian T. DieniD· 2 shared Adam Fries· 1 shared Adeline Mah· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Andrew Altomare

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintFeb 1, 2024

Characterizing and addressing error modes to improve sequencing accuracy

Semyon Kruglyak, Andrew Altomare, Mark R. Ambroso…·Matthew William Kellinger

The paper demonstrates achieving over 70% Q50 accuracy on the AVITI sequencer by improving sequencing quality and mitigating library preparation and analysis errors.

5 citations

experimental assay

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GenomicsNature BiotechnologyPeer-reviewedMay 25, 2023

Sequencing by avidity enables high accuracy with low reagent consumption

Sinan Arslan, Francisco J. Garcia, Minghao Guo…·Jordan M. Neysmith

This paper introduces avidity sequencing, a new chemistry that improves sequencing accuracy and reduces reagent use, enabling applications like single-cell RNA-seq and whole-genome sequencing.

83 citationstop 1%

humanwhole-genome sequencing

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