NeurosciencebioRxivPreprint
Pharmacological inhibition of astrocytic transglutaminase 2 facilitates the expression of a neurosupportive astrocyte reactive phenotype in association with increased histone acetylation
Thomas Delgado, Jacen Emerson, Matthew Hong…·Gail V.W. Johnson
This study shows that inhibiting astrocytic TG2 with VA4 promotes a neurosupportive reactive phenotype through increased histone acetylation and altered transcriptional regulation.
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