Cancer BiologybioRxiv
Inflammatory Recruitment of Healthy Hematopoietic Stem and Progenitor Cells in the Acute Myeloid Leukemia Niche
Ding-Wen Chen, Jian-Meng Fan, Julie M. Schrey…·Peter Kurre
This study shows that healthy hematopoietic stem and progenitor cells (HSPCs) adopt inflammatory gene expression programs in the AML niche, driven by AML-derived extracellular vesicles.