BiochemistrybioRxivPreprint
IRE1α undergoes a dynamic filament assembly cycle governed by unfolded proteins and BiP.
Melissa Mèndez-Moran, Maxence Le-Vasseur, Daniel N. Itzhak…·David A. Agard
This study shows that IRE1α assembly into filaments is dynamically regulated by unfolded proteins and BiP through opposing mechanisms.
DOI 10.64898/2026.10.19.760176