Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Kyle P. Smith, Srinivas Chakravarthy, Amit Rahi…·Dileep Varma
This study uses biophysical and computational methods to characterize the structure of human Cdt1, revealing 'folded over' conformations that suggest a scaffold function.
Florian Kaiser, Maximilian G. Plach, Christoph Leberecht…·V. Joachim Haupt
The paper predicts off-targets of a MAPK14 inhibitor using in silico methods and validates them experimentally, achieving a 46% hit rate.
Florian Kaiser, Maximilian G. Plach, Thomas E. O. Schubert, V. Joachim Haupt
The paper uses AI-based drug screening and biophysics to identify novel PDE2 inhibitors from a chemical library, achieving a 6% hit rate with compounds showing micromolar affinities.