ImmunologyFrontiers in ImmunologyPeer-reviewed
IL-36/IL-36R Signaling Promotes CD4+ T Cell-Dependent Colitis via Pro-Inflammatory Cytokine Production
Maya Maarouf, Michal Kuczma, Timothy Luke Denning
This study shows IL-36γ promotes colitis by enhancing CD4+ T cell cytokine production, specifically IFNγ and TNF, and suggests targeting these cytokines as a therapeutic strategy for IBD.
7 citations