PTPRF is a stress responsive cytoskeletal checkpoint that coordinates metabolic adaptation in hepatocytes and β cells
Mayank Bansal, Wadsen St‐Pierre‐Wijckmans, Javier Negueruela, C. E. Buss, Francisco Ribeiro-Costa, Ao Li, Tiffany Lai, Vishnu M. Nair, Valerie Vandenbempt, Michela Lisjak, Israel Pérez-Chávez, Gayane Hovhannisyan, Daria Ezeriņa, Mehmet Bostancıklıoğlu, Stéphane Demine, , Esteban N. Gurzov
This study identifies PTPRF as a stress-responsive cytoskeletal checkpoint that coordinates metabolic adaptation in hepatocytes and β cells by linking metabolic stress to actin reorganization.
bioRxiv · Sep 7, 2026 · PreprintPhysiology