Esteban N. Gurzov

This study identifies PTPRF as a stress-responsive cytoskeletal checkpoint that coordinates metabolic adaptation in hepatocytes and β cells by linking metabolic stress to actin reorganization.

CellCousin2 improves lineage tracing in zebrafish by reducing background recombination and enhancing ablation efficiency with a new system.

This study shows that loss of PTPRK in hepatocytes reduces steatosis and tumour development in obesity-induced hepatocellular carcinoma.

This study shows that cholangiocytes generate new hepatocytes during zebrafish liver regeneration after partial injury during growth.

This study shows that c-Fos in hepatocytes promotes MASLD and HCC by altering metabolic pathways and signaling networks in obesity.

The paper uses volumetric imaging and single-cell RNAseq to study human dental pulp responses during tooth decay, identifying cellular mechanisms and progression stages.

This study identifies PTPRK's role in promoting hepatocyte metabolic reprogramming in obesity by regulating glycolysis and lipogenesis, with potential therapeutic implications for obesity-related liver diseases.