MicrobiologyJournal of VirologyPeer-reviewed
Conformational dynamics of the HIV-1 envelope glycoprotein from CRF01_AE is associated with susceptibility to antibody-dependent cellular cytotoxicity
Marco Aurelio Díaz-Salinas, Mehdi Benlarbi, Debashree Chatterjee…·James B. Munro
This paper shows HIV-1CRF01_AE Env frequently adopts an open conformation (State 2A) that is susceptible to ADCC, unlike clade A/B Envs which require anti-cluster A antibodies to reach this state.
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