Miao He

A Urinary Metabolomic Signature Associated with Small Intestinal Bacterial Overgrowth in Children with Short Bowel Syndrome

The paper identifies a urinary metabolomic signature linked to small intestinal bacterial overgrowth in children with short bowel syndrome using gas chromatography/mass spectrometry.

Metabolomic, lipidomic, and N-glycomic analyses of a human cell model of Krabbe disease reveal treatable deficits in glycosylation and serine-ceramide metabolism

The paper identifies metabolic deficits in a Krabbe disease model, including enhanced ceramide synthesis and disrupted glycosylation, suggesting new therapeutic targets.

Identification of leptolin as a novel anti-obesity adipokine

This study identifies leptolin as a novel adipokine that improves metabolic status by promoting fat mobilization and energy expenditure, and shows its potential as a therapeutic agent for obesity.

Genomic Prediction Enables Provenance-Aware Selection in 1 Sessile Oak (Quercus petraea) using Foliar Physiological Traits

This study uses genomic prediction to select resilient sessile oak genotypes based on foliar physiological traits, showing high heritability and across-provenance predictability.

Albumin-STING Nanoagonist Reprograms HSPCs to Antitumor Neutrophils Enhancing MHC I-Mediated CD8+ T Cell Immunity

This paper shows that an albumin-STING nanoagonist reprograms hematopoietic stem/progenitor cells into antitumor neutrophils, enhancing CD8+ T cell immunity against tumors.

Novel mouse model reveals neurodevelopmental origin of PMM2-CDG brain pathology

This study creates a mouse model of PMM2-CDG by selectively removing PMM2 from neural precursor cells, revealing cerebellar hypoplasia and ataxia, and showing molecular disturbances in the cerebellum that mirror human disease.