NeuroscienceActa Neuropathologica CommunicationsPeer-reviewed
Loss of BICD2 in muscle drives motor neuron loss in a developmental form of spinal muscular atrophy
Alexander Martin Rossor, James N. Sleigh, Michael Groves…·Giampietro Schiavo
This study shows that loss of BICD2 in muscle drives motor neuron loss in SMALED2 through a non-cell autonomous mechanism involving impaired secretory pathways.