Author

Mikayla Bisignani

University of Pittsburgh

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Neuroscience· 1

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Approach:experimental assay· 1 Organism:mouse· 1

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Karl KandleriD· 1 shared Mahmoud KhaliliD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperNeuroscience

Karl KandlerORCID

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NeurosciencebioRxivPreprintDec 7, 2025

Inner-ear delivery of AAV2-retro robustly labels lateral olivocochlear efferents but results in off-target transfection in the contralateral cochlea and the brain

Mahmoud Khalil, Mikayla Bisignani, Karl Kandler

This study shows that AAV2-retro injected into the inner ear labels the lateral olivocochlear pathway but causes off-target labeling in the contralateral cochlea and brain.

DOI 10.64898/2025.12.03.692215

mouseexperimental assay

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