The gut microbiome promotes mitochondrial respiration in the brain of a Parkinson's disease mouse model
Lívia H. Morais, Linsey Stiles, Milla Freeman, Anastasiya D. Oguienko, Jonathan D. Hoang, Jenny Ji, Jeff J. Jones, Baiyi Quan, Jack Devine, Justin S. Bois, Tsui‐Fen Chou, Joanne Trinh, Martin A. Picard, Viviana Gradinaru, Sarkis K. Mazmanian
This study shows that the gut microbiome increases mitochondrial respiration and oxidative stress in the brain of a Parkinson's disease mouse model, worsening motor symptoms.
npj Parkinson s Disease · Oct 20, 2025Peer-reviewedPhysiology