Author

Ming-Ching Crystal Wen

University of Michigan

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Bioinformatics· 1

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Approach:benchmark study· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

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Andrew Robbins· 1 shared Yiwei LyuiD· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperBioinformatics

Andrew Robbins

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintOct 12, 2026

Beyond the Final Layer: Evaluating Single-Cell Foundation Model Representations for Molecular Prediction

Ming-Ching Crystal Wen, Yiwei Lyu, Andrew Robbins

This paper evaluates the performance of intermediate layers in single-cell foundation models for cell-type and perturbation prediction, finding that some layers perform as well as final layers.

DOI 10.64898/2026.10.05.756880

humanscRNA-seq

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