Molecular BiologybioRxivPreprint
Targeting ABCB4 using mRNA-LNP for the treatment of rare liver diseases
Mohammed Alsuraih, Brianna LaViolette, Guan-Yu Lin…·Shian-Huey Chiang
This study demonstrates that systemic delivery of hABCB4 mRNA LNPs ameliorates liver fibrosis and bile phosphatidylcholine levels in a PFIC3 mouse model.
3 citations