PhysiologybioRxiv
MUC17 is an essential small intestinal glycocalyx component that is disrupted in Crohn's disease
Elena Layunta, Sofia Jäverfelt, Fleur C. van de Koolwijk…·Thaher Pelaseyed
The paper identifies MUC17 as a critical component of the small intestinal glycocalyx that is disrupted in Crohn's disease, leading to bacterial contact and epithelial defects.
DOI 10.1172/jci.insight.181481