Author

Monica Stanciu

Koch Institute for Integrative Cancer Research At MIT

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Developmental Biology· 1

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Approach:experimental assay· 1 Organism:mouse· 1

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Henry M. KronenbergiD· 1 shared Jacqueline A. LeesiD· 1 shared Simona NedelcuiD· 1 shared Tatsuya KobayashiiD· 1 shared

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Developmental BiologybioRxivPreprintMay 10, 2019

Mesenchymal expression of activated K-ras yields Noonan Syndrome-like bone defects that are rescued by mid-gestational MEK inhibition.

Simona Nedelcu, Tatsuya Kobayashi, Monica Stanciu…·Jacqueline A. Lees

This paper generates a mouse model with activated K-ras in mesenchymal progenitors to study Noonan Syndrome-like bone defects and shows that MEK inhibition during mid-gestation rescues these defects.

DOI 10.1101/634840

mouseexperimental assay

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