BioinformaticsbioRxivPreprint
Comprehensive Characterization of Somatic Mutations and Gene Expression on TP53/PTEN DKO Murine Glioblastoma Cell Lines: Insights from Whole-Exome and RNA-seq Analysis
The paper analyzes somatic mutations and gene expression in TP53/PTEN DKO murine glioblastoma cell lines using WES and RNA-seq to reveal early genomic instability and later replication-driven mutations associated with malignancy and TMZ resistance.
DOI 10.64898/2026.11.10.765700