ImmunologybioRxivPreprint
Aged insulin resistant macrophages reveal dysregulated cholesterol biosynthesis, a pro-inflammatory profile and reduced foam cell formation capacity
G Chabrier, S Hobson, N Yuldasheva…·M. C Gage
This study investigates how insulin resistance in aged macrophages affects inflammation, cholesterol biosynthesis, and foam cell formation, finding pro-inflammatory changes and reduced foam cell capacity.
DOI 10.1101/467118