The D614G Mutation Enhances the Lysosomal Trafficking of SARS-CoV-2 Spike
C. Guo, S. J. Tsai, Y. Ai, M. Li, A. Pekosz, A. Cox, N. Atai, S. Gould
This study shows the D614G mutation in SARS-CoV-2 spike enhances lysosomal trafficking and accumulation, contributing to increased infectivity and transmission.
bioRxiv · Dec 8, 2020Cell Biology