Author

N. B. Pattada

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Immunology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

C. H. June· 1 shared C.-A. Assenmacher· 1 shared E. Noguera-Ortega· 1 shared E. Pure· 1 shared J. Schollor· 1 shared L. Huang· 1 shared L. Tood· 1 shared M. Kopp· 1 shared

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2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

C. H. June

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1 paper

Recent·Most cited

ImmunologybioRxivApr 13, 2023

Desmoplastic stroma restricts T cell extravasation and mediates immune exclusion and immunosuppression in solid tumors

Z. Xiao, L. Tood, L. Huang…·E. Pure

This study shows that targeting FAP+CAFs in desmoplastic pancreatic tumors reduces stromal barriers, enhances T cell infiltration, and improves response to immunotherapy.

DOI 10.1038/s41467-023-40850-5

mousebulk RNA-seq

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