Author

N. C. Lima

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

P. H. Huang· 2 shared A. Swain· 1 shared B. A. Howard· 1 shared E. Atkinson· 1 shared F. Calvo· 1 shared J. Burns· 1 shared J. Ning· 1 shared L. Krasny· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

P. H. Huang

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2 papers

Recent·Most cited

Targeting the Src pathway enhances the efficacy of selective FGFR inhibitors in cancers with FGFR3 alterations

N. C. Lima, E. Atkinson, T. D. Bunney, M. Katan, P. H. Huang

This study shows that combining Src pathway inhibitors with FGFR inhibitors improves efficacy in cancers with FGFR3 mutations by overcoming intrinsic resistance.

bioRxiv · Apr 4, 2020Cancer Biology

A mouse SWATH-MS reference spectral library enables deconvolution of species-specific proteomic alterations in human tumour xenografts

L. Krasny, P. Bland, J. Burns, N. C. Lima, P. T. Harrison, L. Pacini, M. L. Elms, J. Ning, V. G. Martinez, Y.-R. Yu, S. E. Acton, P.-C. Ho, F. Calvo, A. Swain, B. A. Howard, , P. H. Huang

The paper develops a mouse SWATH-MS spectral library and a deconvolution method to analyze proteomic changes in human tumor xenografts, revealing host-tumor interactions.

bioRxiv · Feb 3, 2020Biochemistry