P. H. Huang

This study identifies a DNA replication protein signature (SPM6) that improves risk stratification in soft tissue sarcomas when combined with the Sarculator nomogram.

This study shows that combining Src pathway inhibitors with FGFR inhibitors improves efficacy in cancers with FGFR3 mutations by overcoming intrinsic resistance.

The paper develops a mouse SWATH-MS spectral library and a deconvolution method to analyze proteomic changes in human tumor xenografts, revealing host-tumor interactions.

This study investigates how conduit integrity in lymph nodes changes during acute expansion, finding that while the structure is disrupted, FRC-FRC contacts remain intact and antigen flow becomes leaky.

This study evaluates the adequacy of tissue microarrays for assessing TIL burden heterogeneity in leiomyosarcoma and finds that 1-3 cores suffice for ordinal categorization but more are needed for accurate absolute counts.

The paper investigates how primary cilia contribute to kinase inhibitor resistance in cancer by altering cilia structure and function, leading to enhanced hedgehog pathway activation and drug resistance.