Chronic IL-1 exposure drives LNCaP cells to evolve androgen and AR independence
H. Dahl, M. Kanchwala, S. Thomas-Jardin, A. Sandhu, P. Kanumuri, A. F. Nawas, C. Xing, C. Lin, D. E. Frigo, N. Delk
This study shows chronic IL-1 exposure leads to androgen and AR independence in LNCaP prostate cancer cells, promoting castration-resistant prostate cancer development.
bioRxiv · Apr 21, 2020Cancer Biology