Author

S. Thomas-Jardin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

C. Xing· 3 shared H. Dahl· 3 shared M. Kanchwala· 3 shared N. Delk· 3 shared A. Nawas· 2 shared M. Bautista· 2 shared R. Mistry· 2 shared V. Anunobi· 2 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCancer Biology

C. Xing

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3 papers

Recent·Most cited

Cancer BiologybioRxivApr 21, 2020

Chronic IL-1 exposure drives LNCaP cells to evolve androgen and AR independence

H. Dahl, M. Kanchwala, S. Thomas-Jardin…·N. Delk

This study shows chronic IL-1 exposure leads to androgen and AR independence in LNCaP prostate cancer cells, promoting castration-resistant prostate cancer development.

DOI 10.1371/journal.pone.0242970

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivSep 19, 2019

IL-1-conferred gene expression pattern in ERα+ BCa and AR+ PCa cells is intrinsic to ERα- BCa and AR- PCa cells and promotes cell survival

A. Nawas, M. Kanchwala, S. Thomas-Jardin…·N. Delk

The paper identifies a 350-gene set conserved between HR+ and HR- BCa/PCa cells that promotes HR-independent survival and treatment resistance.

DOI 10.1186/s12885-020-6529-9

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivSep 19, 2019

RELA is Sufficient to Mediate Interleukin-1 (IL-1) Repression of Androgen Receptor Expression and Activity in LNCaP Disease Progression Model

S. Thomas-Jardin, H. Dahl, M. Kanchwala…·N. Delk

This study shows that RELA mediates IL-1 repression of AR mRNA and activity in PCa cells, with stronger effects in castration-resistant sublines.

DOI 10.1002/pros.23925

humanbulk RNA-seq

𝕏 PostBluesky