Cancer BiologybioRxiv
Discovery of an AKT Degrader with Prolonged Inhibition ofDownstream Signaling
I. You, E. Erickson, K. Donovan…·A. Toker
This study develops INY-03-041, a pan-AKT degrader that shows prolonged inhibition of AKT and downstream signaling effects compared to traditional inhibitors.
DOI 10.1016/j.chembiol.2019.11.014