Cell BiologybioRxiv
SILAC phosphoproteomics reveals unique signaling circuits in CAR-T cells and the inhibition of B cell-activating phosphorylation in target cells
A. A. Griffith, K. P. Callahan, N. G. King…·A. R. Salomon
The paper uses SILAC phosphoproteomics to compare signaling changes in CAR-T cells and target B cells, finding unique phosphorylation patterns in CAR-T cells and reduced B cell receptor signaling in target cells.
DOI 10.1021/acs.jproteome.1c00735