N. Grandvaux

This paper shows that defective influenza A virus RNAs trigger MAVS-dependent upregulation of HLA class I proteins, which may aid viral evasion of innate immunity.

This study identifies thousands of reversible Cys oxidation sites in vivo using a bioswitch method and mass spectrometry, revealing redox-dependent inhibition of STING through Cys206 oxidation.

This study shows DUSP1 promotes apoptosis and inhibits cell migration during RSV and SeV infection but does not affect JIP1-protected cytokine responses.

The paper determines the crystal structures of IRF9-IAD and its complex with STAT2-CCD, revealing structural basis for ISGF3 formation and ISG regulation.